科学研究情况简介 |
【近年来主要研究课题】 1. 纳米递药系统；2. 生物制药的研发；3. 生物医用材料 【近年来主要论文代表作】*为通讯作者 (1) Huiyan Ying, Juan Zhou*, Mingyu Wang, Dandan Su, Qiaoqiao Ma, Guozhong Lv and Jinghua Chen*. In Situ Formed Collagen-Hyaluronic Acid Hydrogel as Biomimetic Dressing for Promoting Spontaneous Wound Healing, Materials Science and Engineering: C, 2019, 101, 487-498. (2) Dandan Su, Juan Zhou*, Kamel S.Ahmed, Qiaoqiao Ma, Guozhong Lv and Jinghua Chen*. Fabrication and characterization of collagen-heparin-polypyrrole composite conductive film for neural scaffold, International Journal of Biological Macromolecules, 2019, 129, 895-903. (3) Safia Naz, Muhammad Shamoon, Rui Wang, Li Zhang, Juan Zhou* and Jinghua Chen*. Advances in Therapeutic Implications of Inorganic Drug Delivery Nano-Platforms for Cancer, International Journal of Molecular Science, 2019, 20, 965-982. (4) Safia Naz, Mingyu Wang, Yuning Han, Bin Hu, Liping Teng, Juan Zhou*, Huijie Zhang* and Jinghua Chen. Enzyme Responsive Mesoporous Silica Nanoparticles for Tumor Cells and Mitochondria Multistage-Targeted Drug Delivery, International Journal of Nanomedicine, 2019, 14, 2533-2542. (5) Sheng Xie, Juan Zhou, Xuan Chen, Na Kong, Yanmiao Fan, Yang Zhang, Gerry Hamme, David G. Castner, Olof Ramström* and Mingdi Yan*. A versatile catalyst-free perfluoroaryl azide–aldehyde–amine conjugation reaction, Materials Chemistry Frontiers, 2019，doi:10.1039/C8QM00516H. (6) Juan Zhou, Mingyu Wang, Huiyan Ying, Dandan Su, Huijie Zhang, Guozhong Lv and Jinghua Chen*. Extracellular Matrix Component Shelled Nanoparticles as Dual Enzyme-Responsive Drug Delivery Vehicles for Cancer Therapy, ACS Biomaterials Science & Engineering, 2018, 4 (7), 2404-2411. (7) Juan Zhou, Huiyan Ying, Mingyu Wang, Dandan Su, Guozhong Lv and Jinghua Chen*. Dual layer collagen-GAG conduit that mimic vascular scaffold and promote blood vessel cells adhesion, proliferation and elongation, Materials Science and Engineering: C, 2018, 92 (1), 447-452. (8) Zhi Cai，Liping Teng，Juan Zhou，Yishu Yan*，Yan Zhang，Guozhong Lv，Jinghua Chen*. Design and synthesis of a native heparin disaccharide grafted poly‑2‑aminoethyl methacrylate glycopolymer for inhibition of melanoma cell metastasis, International Journal of Biological Macromolecules, 2018, doi: 10.1016/j.ijbiomac.2018.11.255. (9) Na Kong, Sheng Xie, Juan Zhou, Margarita Menendez, Dolores Solis, JaeHyeung Park, Giampiero Proietti, Olof Ramström* and Mingdi Yan*. Catalyst-Free Cycloaddition Reaction for the Synthesis of Glyconanoparticles， ACS Applied Materials & Interfaces, 2016, 8 (41), 28136–28142. (10)Qi Cai, Juan Zhou, Weiping Zhu*, Yufang Xu and Xuhong Qian. Fluorescent and MRI Bimodal Imaging Agent for Tumor Hypoxia， Nanomedicine: Nanotechnology, Biology and Medicine, 2016, 12 (2), 506-506. (11)Juan Zhou, Núria Butchosa, H. Surangi N. Jayawardena, JaeHyeung Park, Qi Zhou, Mingdi Yan* and Olof Ramström*. Synthesis of Multifunctional Cellulose Nanocrystals for Lectin Recognition and Bacterial Imaging， Biomacromolecules, 2015, 16 (4), 1426-1432. (12) Juan Zhou, Nanjing Hao, Thareendra De Zoyza, Mingdi Yan* and Olof Ramström*. Lectin-Gated, Mesoporous, Photofunctionalized Glyconanoparticles for Glutathione-Responsive Drug Delivery， Chemical Communications, 2015, 51, 9833-9836. (13) Juan Zhou, Kalana Jayawardana, Yansong Ren, Na Kong, Mingdi Yan* and Olof Ramström*. Trehalose-Conjugated Mesoporous Silica Nanoparticles for Efficient Delivery of Isoniazid into Mycobacteria， ACS Biomaterials Science & Engineering, 2015, 1 (12), 1250-1255. (14) Na Kong, Juan Zhou, JaeHyeung Park, Sheng Xie, Olof Ramström* and Mingdi Yan*. Quantitative Fluorine NMR (19F qNMR) to Determine Carbohydrate Density on Glyconanomaterials Synthesized from Perfluorophenyl Azide-Functionalized Silica Nanoparticles by Click Reaction， Analytical Chemistry, 2015, 87 (18), 9451-9458. (15) Juan Zhou, Núria Butchosa, H. Surangi N. Jayawardena, Qi Zhou, Olof Ramström* and Mingdi Yan*. Glycan-Functionalized Fluorescent Chitin Nanocrystals for Biorecognition Applications， Bioconjugate Chemistry, 2014, 25 (4), 640-643. |
